Although no detailed pathophysiology mechanism is known, a generally accepted concept is that allergic reactions trigger obesity cell degranulation, resulting in numerous inflammatory agents affecting coronary arteries and indicating angina and myocardial infarctionAllergic angina, called Kounis syndrome, is an acute coronary syndrome caused by allergies, including in-stent thrombosis from anaphylactoid processes. It is called Kounis syndrome when anaphylaxis is clinically related to myocardial ischemia as well as fall disorders, including atrial arrhythmia, ventricular arrhythmia, and T-wave abnormalities.Some anaphylactic reactions to cephalosporins, such as ceftazidim, ceftriaxone, cefazoline, and ceproxime, cause certain types of vasospastic myocardial ischemia or infraction called Kounis syndrome.N English J Med 2023; 389:263-72.It has also been reported in Korea.2012 JMed Korea; 82(6): 724-728.REF. UpTo Date 2023.08.04 N Engl J Med 2023; 389:263-72.J Med in South Korea in 2012; 82(6): 724-728.
